Short handed - Strategy change as player numbers change?

[excel]

When playing at a standard 6 player table, as with any game players leave and join, quiet often the table will carry on playing with 5 or 4 players,

Do good players actively adjust there play to this lower number of players, particularly pre flop where hands like Ax surely become more profitable in the OC or button, whereas a tight player may fold these if 6 players at the table.


Also, say Im first in with a raise on the button with A7 on a 4 player table, is that in the long term likelt to be the same profitability (or should I be saying EV) as if I did the same play in a 6 player game, 1st in on the button.