At what point?
At risk of making myself out to be far more on an expert than I actually am ...
For me, it is less a matter of "Oh, now there are five players left and blinds have gone up, time to throw the aggressive switch" and more of a gradual progression from very-tight at the beginning to (hopefully) stealing blinds left and right in heads up play. Perhaps think of it of increasing in 10% increments for each player that is knocked out.
One other observations. I find play changes noticeably as you get to within one/two/three players of the money, depending on size of the field. No one wants to have played for that long, and end up with nothing so close to the promised land. This can be a prime time to make some moves -- with the obvious caveat that if these go wrong, it can be you who ends up finishing so close but yet so far!
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